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A fine LINE-1 in mouse embryonic chromatin regulation

The functional role of repetitive elements in mammalian genomes is still largely unexplored. A new study provides evidence that LINE-1 retrotransposons regulate chromatin dynamics and are essential for normal embryonic development in mice.

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Author information

Affiliations

  1. Edward J. Grow is at the Department of Oncological Sciences, Huntsman Cancer Institute and Howard Hughes Medical Institute, Salt Lake City, Utah, USA.

    • Edward J Grow

Authors

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Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Edward J Grow.