Abstract
Foetal rat diaphragm muscle fibres are sensitive to acetylcholine (ACh) over their entire length1. As the animal matures the sensitivity recedes from the tendon area towards the middle, end-plate region, of the fibres. Three to four weeks after birth the sensitive area is restricted to the end-plate region.
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References
Diamond, J., and Miledi, R., J. Physiol., 162, 393 (1962).
Axelsson, J., and Thesleff, S., J. Physiol., 149, 178 (1959).
Redfern, P., and Thesleff, S., Acta Physiol. Scand., 82, 70 (1971).
Liley, A. W., J. Physiol., 132, 650 (1956).
Harris, J. B., Marshall, M. W., and Wilson, P., J. Physiol., 229, 751 (1973).
Redfern, P., J. Physiol., 209, 701 (1970).
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HARRIS, J., MARSHALL, M. Tetrodotoxin-resistant Action Potentials in Newborn Rat Muscle. Nature New Biology 243, 191–192 (1973). https://doi.org/10.1038/newbio243191a0
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DOI: https://doi.org/10.1038/newbio243191a0
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