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Cell-free Synthesis of Histories directed by Messenger RNA from Sea Urchin Embryos

Nature New Biology volume 241, pages 272–274 (1973)Cite this article

Abstract

A PROMINENT class Of light polyribosomes in cleaving sea urchin embryos has been shown to synthesize histones1–4. A rapidly-labelled “9S” RNA having the characteristics of mRNA can be isolated from these polyribosomes5–7. We present here evidence that this 9S RNA programmes the cell-free synthesis of all the major histone classes. A similar class of mRNA obtained from S-phase HeLa polyribosomes8–9 also promotes in vitro histone synthesis10.

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Author notes

  1. P. R. GROSS

    Present address: Department of Biology, University of Rochester, Rochester, NY, 14627

Authors and Affiliations

  1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139

    K. GROSS, J. RUDERMAN, M. JACOBS-LORENA, C. BAGLIONI & P. R. GROSS

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  1. K. GROSS
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  2. J. RUDERMAN
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  3. M. JACOBS-LORENA
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  4. C. BAGLIONI
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  5. P. R. GROSS
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GROSS, K., RUDERMAN, J., JACOBS-LORENA, M. et al. Cell-free Synthesis of Histories directed by Messenger RNA from Sea Urchin Embryos. Nature New Biology 241, 272–274 (1973). https://doi.org/10.1038/newbio241272a0

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