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Stereoselective Differentiation between Ribonucleosides and Deoxynucleosides by Reaction with the Copper(II) Acetate Dimer

Nature New Biology volume 239, pages 237–240 (1972)Cite this article

Abstract

METAL ions are involved in the distinction between ribonucleosides and deoxynucleosides in biochemical processes. For example, RNA polymerase incorporates only ribonucleotides into RNA in the presence of magnesium ions, whereas manganese ions may bring about the misincorporation of deoxy-nucleotides1. Therefore it is of interest to examine ways in which metal ions can distinguish between these two types of molecules.

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Author notes

  1. N. A. BERGER

    Present address: Division of Hematology, Washington University School of Medicine, St Louis, Missouri, 63110

Authors and Affiliations

  1. National Institutes of Health, Gerontology Research Center, Baltimore City Hospitals, Baltimore, Maryland, 21224

    N. A. BERGER, E. TARIEN & G. L. EICHHORN

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  1. N. A. BERGER
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  2. E. TARIEN
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  3. G. L. EICHHORN
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BERGER, N., TARIEN, E. & EICHHORN, G. Stereoselective Differentiation between Ribonucleosides and Deoxynucleosides by Reaction with the Copper(II) Acetate Dimer. Nature New Biology 239, 237–240 (1972). https://doi.org/10.1038/newbio239237a0

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