Abstract
THE tetrameric phage Qβ replicase is composed of three pre-existing E. coli proteins in addition to the phage coded synthetase1,2. The host subunits also appear to form part of the f2 replicase3. We have found that the cistron specific factor i4 cross reacts immunologically and coelectrophoresis on SDS-acrylamide gel with the largest replicase subunit.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
We are sorry, but there is no personal subscription option available for your country.
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kondo, M., Gallerani, R., & Weissmann, C., Nature, 228, 525 (1970).
Kamen, R., Nature, 228, 527 (1970).
Fedoroff, N. V., & Zinder, N. D., Proc. US Nat. Acad. Sci., 68, 1888 (1971).
Groner, Y., Pollack, Y., Berissi, H., and Revel, M., Nature (this issue).
Ouchterlony, O., Acta Pathol. Microbiol. Scand., 25, 186 (1948).
Laemmli, U. K., Nature, 227, 680 (1970).
Kolakofsky, D., & Weissmann, C., Nature New Biology, 231, 42 (1971).
Eggen, K., & Nathans, D., Fed. Proc., 26, 449 (1967).
Vinuela, E., Algranati, I. D., & Ochoa, S., Europ. J. Biochem., 1, 3 (1967).
Lodish, H., J. Mol. Biol., 50, 689 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GRONER, Y., SCHEPS, R., KAMEN, R. et al. Host Subunit of Qβ Replicase is Translation Control Factor i. Nature New Biology 239, 19–20 (1972). https://doi.org/10.1038/newbio239019a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/newbio239019a0
This article is cited by
-
Determinant of cistron specificity in bacterial ribosomes
Nature (1975)
-
An SV40-induced initiation factor for protein synthesis concerned with the regulation of permissiveness
Nature (1974)
-
Isolation of an inhibitor protein of E. coli RNA polymerase from T7 phage infected cell
Nature (1974)
-
Subunit complex III-IV as the nucleotide binding site of Qβ replicase
Nature (1974)