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Haemoglobin Polymorphism in the Rhesus Macaque

Abstract

INTRASPECIFIC polymorphism of the principal haemoglobin component is common among macaque monkeys1–3 and other non-human primates4–9, but although electrophoretically demonstrable it has not been found in populations of rhesus monkeys (M. mulatto)10,11. Using the technique of isoelectric focusing in acrylamide gel, I have found variant haemoglobins in many samples of rhesus red blood cell haemolysates. The detection of these variants is apparently a result of the greatly increased resolution of the isoelectric focusing method as compared with the older electrophoretic methods.

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References

  1. Barnicott, N. A., Huens, E. R., and Jolly, C. J., Proc. Roy. Soc, 105, B, 224 (1966).

    Google Scholar 

  2. Kunkel, H. G., Ceppellini, R., Muller-Eberhard, V., and Wolf, J., J. Clin. Invest., 36, 1615 (1957).

    Article  CAS  Google Scholar 

  3. Kitchen, H., Eaton, J. W., and Stenger, V. G., Arch. Biochem. Biophys., 123, 227 (1968).

    Article  CAS  Google Scholar 

  4. Buettner-Janusch, J., Folia Primatol., 1, 73 (1963).

    Article  Google Scholar 

  5. Boyer, S. H., Noyes, A. N., Vrablik, G. R., Donaldson, L. J., Shaefer, jun., E. W., Gray, C. W., and Thurman, T. F., Science, 171, 182 (1971).

    Article  CAS  Google Scholar 

  6. Hoffman, H. A., Gottlieb, A. J., and Wisecup, W. G., Science, 156, 944 (1967).

    Article  CAS  Google Scholar 

  7. Jacob, G. F., and Tappen, N. C., Nature, 280, 241 (1957).

    Article  Google Scholar 

  8. Buettner-Janusch, J., and Buettner-Janusch, V., Evolutionary and Genetic Biology of the Primates (edit. by Buettner-Janusch), 2, 75 (Academic Press, New York, 1964).

    Book  Google Scholar 

  9. Barnicott, N. A., and Jolly, C. J., Nature, 210, 640 (1966).

    Article  Google Scholar 

  10. Buettner-Janusch, J., Twichell, J. B., Yuan Shu-Wong, B., and van Wagenen, G., Nature, 192, 948 (1961).

    Article  CAS  Google Scholar 

  11. Gottlieb, A. J., and van Lanker, S. L., Nature, 200, 900 (1963).

    Article  CAS  Google Scholar 

  12. Bucci, E., and Fronticelli, C., J. Biol. Chem., 240, PC551 (1963).

    Google Scholar 

  13. Schroeder, W. A., Husman, T. H. S., Shelton, J. R., Shelton, J. B., Kleihauer Dozy, A. M., and Robberson, B., Proc. US Nat. Acad. Sci., 60, 537 (1968).

    Article  CAS  Google Scholar 

  14. Huisman, T. H. J., Wilson, J. B., and Adams, H. R., Arch. Biochem. Biophys., 121, 528 (1967).

    Article  CAS  Google Scholar 

  15. Popp, R. A., J. Mol. Biol., 29, 9 (1967).

    Article  Google Scholar 

  16. Lehmann, H., and Carrell, R. W., Brit. Med. J., 4, 748 (1968).

    Article  CAS  Google Scholar 

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BASCH, R. Haemoglobin Polymorphism in the Rhesus Macaque. Nature New Biology 238, 238–240 (1972). https://doi.org/10.1038/newbio238238a0

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