Abstract
IT is well known that the active tetanic tension of a living striated muscle fibre decreases linearly with increase of fibre length beyond its slack length1,2, and this has been explained2 by the decreased number of interacting sites between thick (myosin-containing) and thin (actin-containing) filaments. Skinned fibres3 have been shown to behave similarly at high concentrations of calcium4. But examination of the mechanical properties, of partially activated skinned muscle fibres showed that the isometric tension increased with the increase of fibre length beyond its slack length if contraction was induced by a low concentration of calcium ions.
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ENDO, M. Stretch-induced Increase in Activation of Skinned Muscle Fibres by Calcium. Nature New Biology 237, 211–213 (1972). https://doi.org/10.1038/newbio237211a0
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DOI: https://doi.org/10.1038/newbio237211a0
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