Abstract
PICROTOXIN has been shown to antagonize specifically the inhibitory action of λ-aminobutyric acid (GABA) as opposed to glycine (Gly) on cells of the cuneate nucleus, either spontaneously active or excited by peripheral stimulation1. Bicucul-line also seems to be a specific antagonist of the depressant action of GABA in several regions of the mammalian nervous system2, although probably not in others3.
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References
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KELLY, J., RENAUD, L. Post-synaptic Inhibition in the Cuneate blocked by GABA Antagonist. Nature New Biology 232, 25–26 (1971). https://doi.org/10.1038/newbio232025a0
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DOI: https://doi.org/10.1038/newbio232025a0
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