Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

NSAIDs and the risk of acute myocardial infarction

Nature Clinical Practice Rheumatology volume 3, pages 202–203 (2007)Cite this article

boxed-textSingh G et al. (2006) Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis. Arthritis Res Ther 8: R153

Further observational studies are needed to characterize the cardiovascular safety of traditional NSAIDs

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Kearney PM et al. (2006) Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ 332: 1302–1308

    Article  CAS  Google Scholar 

  2. Hernández-Díaz S et al. (2006) Non-steroidal anti-inflammatory drugs and the risk of acute myocardial infarction. Basic Clin Pharmacol Toxicol 98: 266–274

    Article  Google Scholar 

  3. McGettigan P and Henry D (2006) Cardiovascular risk and inhibition of cyclo-oxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclo-oxygenase 2. JAMA 296: 1633–1644

    Article  CAS  Google Scholar 

  4. Cannon CP et al. (2006) Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet 368: 1771–1781

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Jasmine Farsarakis, Associate Editor, Nature Clinical Practice.

Author information

Authors and Affiliations

  1. LA García Rodríguez is the Director of Epidemiology and A González-Pérez is an Epidemiologist at the Spanish Centre for Pharmacoepidemiologic Research in Madrid, Spain.,

    Luis A García Rodríguez & Antonio González-Pérez

Authors
  1. Luis A García Rodríguez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Antonio González-Pérez
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Luis A García Rodríguez.

Ethics declarations

Competing interests

CEIFE has received in the past unrestricted research grants from various manufacturers of NSAIDs, including Novartis, Pharmacia and Pfizer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

García Rodríguez, L., González-Pérez, A. NSAIDs and the risk of acute myocardial infarction. Nat Rev Rheumatol 3, 202–203 (2007). https://doi.org/10.1038/ncprheum0459

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncprheum0459

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing