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Can serum pentosidine levels predict risk of vertebral fracture in patients with type 2 diabetes mellitus?

Nature Clinical Practice Endocrinology & Metabolism volume 4, pages 366–367 (2008)Cite this article

Yamamoto M et al. (2008) Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab 93: 1013–1019

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References

  1. Saito M et al. (2006) Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats. Osteoporos Int 17: 1514–1523

    Article  CAS  Google Scholar 

  2. Odetti P et al. (2005) Advanced glycation end products and bone loss during aging. Ann NY Acad Sci 1043: 710–717

    Article  CAS  Google Scholar 

  3. Viguet-Carrin S et al. (2006) Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 39: 1073–1079

    Article  CAS  Google Scholar 

  4. Saito M et al. (2006) Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls. Calcif Tissue Int 79: 160–168

    Article  CAS  Google Scholar 

  5. Shiraki M et al. (2008) Nonenzymatic collagen cross-links induced by glycoxidation (pentosidine) predicts vertebral fractures. J Bone Miner Metab 26: 93–100

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.

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  1. Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8020, USA karl.insogna@yale.edu

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  1. K Insogna is a Professor of Medicine at Yale University School of Medicine, New Haven, CT, USA.,

    Karl Insogna

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Insogna, K. Can serum pentosidine levels predict risk of vertebral fracture in patients with type 2 diabetes mellitus?. Nat Rev Endocrinol 4, 366–367 (2008). https://doi.org/10.1038/ncpendmet0835

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