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Does clopidogrel pretreatment counteract the benefits of off-pump CABG surgery?

Nature Clinical Practice Cardiovascular Medicine volume 3, pages 530–531 (2006)Cite this article

boxed-textKapetanakis EI et al. (2006) Effect of clopidogrel premedication in off-pump cardiac surgery: are we forfeiting the benefits of reduced hemorrhagic sequelae? Circulation 113: 1667–1674

Treatment with clopidogrel before CABG surgery is associated with an increased risk of bleeding whether an off-pump or traditional on-pump bypass is performed

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Acknowledgements

The synopsis was written by Hannah Camm, Editor, Nature Clinical Practice.

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Authors and Affiliations

  1. Director of Cardiovascular Genomics and Cardiovascular Research at the Center for Health Research and Rural Advocacy,

    Kimberley Skelding & Peter B Berger

  2. Associate Chief Research Officer for Clinical Studies at Geisinger Medical Center, Danville, PA, USA

    Kimberley Skelding & Peter B Berger

Authors
  1. Kimberley Skelding
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  2. Peter B Berger
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Correspondence to Kimberley Skelding.

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Competing interests

The Duke University catheterization laboratory conference that PB Berger directs has received unrestricted educational grants from Sanofi Aventis, Lilly, Sankyo, Datascope, Johnson and Johnson, The Medicine Company, Boston Scientific and Medtronic. He has received research support from Boehringer Ingelheim, Conor, Cardiokinetix and Guilford. He has spoken at scientific symposia supported by Bristol-Myers Squibb, Sanofi Aventis, Arginox and Schering Plough. He has served as a consultant to Johnson and Johnson, Boston Scientific, Genetech and Guilford. K Skelding declared she has no competing interests.

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Skelding, K., Berger, P. Does clopidogrel pretreatment counteract the benefits of off-pump CABG surgery?. Nat Rev Cardiol 3, 530–531 (2006). https://doi.org/10.1038/ncpcardio0652

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