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Should prophylactic amiodarone therapy be used to prevent atrial tachyarrhythmia after cardiac surgery?

Nature Clinical Practice Cardiovascular Medicine volume 3, pages 422–423 (2006)Cite this article

boxed-textMitchell LB et al. (2005) Prophylactic oral amiodarone for the prevention of arrhythmias that begin early after revascularization, valve replacement, or repair. PAPABEAR: a randomized controlled trial. JAMA 294: 3093–3100

Amiodarone is safe and effective in preventing postoperative atrial tachyarrhythmia; whether this translates to significant reductions in hospital stay or morbidity is not known

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References

  1. Asabo JD et al. (2005) Amiodarone prophylaxis reduces major cardiovascular morbidity and length of stay after cardiac surgery. Ann Intern Med 143: 327–336

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Acknowledgements

The synopsis was written by Hannah Camm, Associate Editor, Nature Clinical Practice.

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Authors and Affiliations

  1. staff cardiac electrophysiologist in the Divison of Cardiology, Southlake Regional Health Centre, Newmarket, ON, Canada

    Atul Verma

  2. scientist and assistant professor,

    Subodh Verma, Lee Errett & Paul Dorian

  3. professor and Chief of the Division of Cardiac Surgery,

    Subodh Verma, Lee Errett & Paul Dorian

  4. Division of Cardiac Surgery, professor, St. Michael's Hosptial, University of Toronto, Toronto, ON, Canada

    Subodh Verma, Lee Errett & Paul Dorian

Authors
  1. Atul Verma
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  2. Subodh Verma
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  3. Lee Errett
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  4. Paul Dorian
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Corresponding author

Correspondence to Subodh Verma.

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The authors declare no competing financial interests.

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Verma, A., Verma, S., Errett, L. et al. Should prophylactic amiodarone therapy be used to prevent atrial tachyarrhythmia after cardiac surgery?. Nat Rev Cardiol 3, 422–423 (2006). https://doi.org/10.1038/ncpcardio0629

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  • DOI: https://doi.org/10.1038/ncpcardio0629

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