Figure 8: Time-resolved map of insulin secretion pathways in beta cells.

From: Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

figure 8
Figure 8

Assembly of insulin secretion pathways from multiple databases. Phosphosites are labeled according to their highest phosphorylation peak, as revealed in our phosphoproteomics data set (see legend). New regulatory phosphoproteins are labelled in green. Proteins significantly modulated in diabetic islets have a red border.