Figure 6: Successful fetal development of chimeric mosaic embryos.

From: Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential

Figure 6: Successful fetal development of chimeric mosaic embryos.
Figure 6

Chimeras that had been transferred to recipient females were recovered at E13.5. (a) Examples of whole-mount images (Histone H2B-GFP expression marks the reversine-treated clone). Scale bars, 2 mm. Note: the fetuses were imaged using different microscopes, the difference in colour is reflective of the microscope used, not differences between the two groups. (b) Fetal and placental biopsies from the E13.5 conceptuses shown in A. Scale bars, 100 μm. In all cases, where a Histone H2B-GFP clone was present, the cells were evenly distributed throughout the tissues. Both placental and fetal biopsy findings were consistent with the whole-mount GFP images.