As the field of chemical biology matures, its practitioners are tackling ever more sophisticated biological problems. Chemical approaches, both synthetic and analytical, provide researchers with powerful new technologies to perturb, dissect and even reconstruct complex biological systems. Here we discuss the special challenges and opportunities confronted at the burgeoning interface of chemical and systems biology.
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Simon, G., Cravatt, B. Challenges for the 'chemical-systems' biologist. Nat Chem Biol 4, 639–642 (2008). https://doi.org/10.1038/nchembio1108-639
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DOI: https://doi.org/10.1038/nchembio1108-639
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