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From yeast to alkaloids

Nature Chemical Biology volume 4, pages 524–525 (2008)Cite this article

Alkaloids, which include caffeine and morphine, are a large class of pharmacologically active plant compounds that are often difficult to chemically synthesize. Incorporation of benzylisoquinoline alkaloid pathways in yeast will facilitate the production of natural and non-natural alkaloids.

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Figure 1: Pathways for the production of BIAs.

References

  1. Hawkins, K.M. & Smolke, C.D. Nat. Chem. Biol. 4, 564–573 (2008).

    Article  CAS  Google Scholar 

  2. Khosla, C. & Keasling, J.D. Nat. Rev. Drug Discov. 2, 1019–1025 (2003).

    Article  CAS  Google Scholar 

  3. Minami, H. et al. Proc. Natl. Acad. Sci. USA 105, 7393–7398 (2008).

    Article  CAS  Google Scholar 

  4. Martin, V.J.J., Pitera, D.J., Withers, S.T., Newman, J.D. & Keasling, J.D. Nat. Biotechnol. 21, 796–802 (2003).

    Article  CAS  Google Scholar 

  5. Ro, D.-K. et al. Nature 440, 940–943 (2006).

    Article  CAS  Google Scholar 

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  1. Jay Keasling is in the Departments of Chemical Engineering and Bioengineering, USA The Physical Biosciences Division, University of California, Berkeley, California 94720, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA, and the Joint BioEnergy Institute, 5885 Hollis, Emeryville, California 94608, USA. keasling@berkeley.edu,

    Jay Keasling

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Keasling, J. From yeast to alkaloids. Nat Chem Biol 4, 524–525 (2008). https://doi.org/10.1038/nchembio0908-524

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