In the competition for control of iron between Mycobacterium tuberculosis and host cells, very little is understood about how these bacteria use small-molecule siderophores to obtain iron. A mechanism is now shown for intracellular iron acquisition by mycobacterial lipophilic siderophores.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Iron homeostasis in Mycobacterium tuberculosis is essential for persistence
Scientific Reports Open Access 26 November 2018
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Luo, M., Fadeev, E.A. & Groves, J.T. Nat. Chem. Biol. 1, 149–153 (2005).
De Voss, J.J. et al. J. Bacteriol. 181, 4443–4451 (1999).
De Voss, J.J. et al. Proc. Natl. Acad. Sci. USA 97, 1252–1257 (2000).
Gobin, J. & Horwitz, M.A. J. Exp. Med. 183, 1527–1532 (1996).
Ratledge, C. Iron, mycobacteria and tuberculosis. Tuberculosis (Edinb.) 84, 110–130 (2004).
Ferreras, J.A. et al. Nat. Chem. Biol. 1, 29–32 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Barry, C., Boshoff, H. Getting the iron out. Nat Chem Biol 1, 127–128 (2005). https://doi.org/10.1038/nchembio0805-127
Issue Date:
DOI: https://doi.org/10.1038/nchembio0805-127
This article is cited by
-
Iron homeostasis in Mycobacterium tuberculosis is essential for persistence
Scientific Reports (2018)
