The zebrafish has provided insights into the mechanisms of vertebrate development, in large part due to its amenability to optical imaging. While fluorescent proteins and other genetically encoded reporters are valuable imaging tools, synthetic probes can reveal dynamical processes such as glycan biosynthesis that are undetectable by conventional methods.
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Chen, J. Fish 'n clicks. Nat Chem Biol 4, 391–392 (2008). https://doi.org/10.1038/nchembio0708-391
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DOI: https://doi.org/10.1038/nchembio0708-391