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AMPylation is a new post-translational modiFICation

Nature Chemical Biology volume 5, pages 378–379 (2009)Cite this article

A class of proteins containing domains that are evolutionarily conserved among prokaryotes and eukaryotes was recently found to mediate post-translational AMP addition—a new protein modification called AMPylation. Similarities to the post-translational modification phosphorylation suggest that AMPylation may be an important regulatory mechanism.

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Figure 1: Similarities between phosphorylation and AMPylation of proteins.

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Authors and Affiliations

  1. Melanie L. Yarbrough and Kim Orth are in the Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas Texas, USA. kim.orth@utsouthwestern.edu,

    Melanie L Yarbrough & Kim Orth

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  1. Melanie L Yarbrough
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  2. Kim Orth
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Yarbrough, M., Orth, K. AMPylation is a new post-translational modiFICation. Nat Chem Biol 5, 378–379 (2009). https://doi.org/10.1038/nchembio0609-378

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