A high-throughput one-hybrid screen identifies a regulator of the Arabidopsis thaliana circadian gene CIRCADIAN CLOCK ASSOCIATED1 (CCA1). CCA1 HIKING EXPEDITION (CHE) represses CCA1 and physically interacts with TIMING OF CAB1 (TOC1) to link TOC1 with CCA1 in the clock.
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References
Young, M.W. & Kay, S.A. Nat. Rev. Genet. 2, 702–715 (2001).
Dodd, A.N. et al. Science 318, 1789–1792 (2007).
O'Neill, J.S., Maywood, E.S., Chesham, J.E., Takahashi, J.S. & Hastings, M.H. Science 320, 949–953 (2008).
Robertson, F.C., Skeffington, A.W., Gardner, M.J. & Webb, A.A.R. Plant Mol. Biol. 69, 419–427 (2009).
Ouyang, Y., Andersson, C.R., Kondo, T., Golden, S.S. & Johnson, C.H. Proc. Natl. Acad. Sci. USA 95, 8660–8664 (1998).
Dodd, A.N. et al. Science 309, 630–633 (2005).
Turek, F.W. et al. Science 308, 1043–1045 (2005).
Pruneda-Paz, J.L., Breton, G., Para, A. & Kay, S.A. Science 323, 1481–1485 (2009).
Gong, W. et al. Plant Physiol. 135, 773–782 (2004).
Locke, J.C.W. et al. Mol. Sys. Biol. 1, 2005.0013 (2005)
Harmer, S.L. et al. Science 290, 2110–2113 (2000).
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Robertson, F., Webb, A. Revolutionary functional genomics liberates CHE. Nat Chem Biol 5, 276–277 (2009). https://doi.org/10.1038/nchembio0509-276
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DOI: https://doi.org/10.1038/nchembio0509-276
