Model systems have evolved with the times, making use of modern biological methods and incorporating biological complexity. This evolution has increased the relevance of models as tools for studying biology.
Access options
Subscribe to Journal
Get full journal access for 1 year
70,80 €
only 5,90 € per issue
All prices include VAT for France.
Rent or Buy article
Get time limited or full article access on ReadCube.
from$8.99
All prices are NET prices.
References
- 1.
Jencks, W.P. & Page, M.I. Biochem. Biophys. Res. Commun. 57, 887–892 (1974).
- 2.
Breslow, R. Chem. Rec. 1, 3–11 (2001).
- 3.
Ma, J.C. & Dougherty, D.A. Chem. Rev. 97, 1303–1324 (1997).
- 4.
Meyer, E.A., Castellano, R.K. & Diederich, F. Angew. Chem. Int. Ed. 42, 1210–1250 (2003).
- 5.
Dougherty, D.A. Science 271, 163–168 (1996).
- 6.
Gallivan, J.P. & Dougherty, D.A. Proc. Natl. Acad. Sci. USA 96, 9459–9464 (1999).
- 7.
Shi, Z., Olson, C.A. & Kallenbach, N.R. J. Am. Chem. Soc. 124, 3284–3291 (2002).
- 8.
Tsou, L.K., Tatko, C.D. & Waters, M.L. J. Am. Chem. Soc. 124, 14917–14921 (2002).
- 9.
Tatko, C.D. & Waters, M.L. Protein Sci. 12, 2443–2452 (2003).
- 10.
Tatko, C.D. & Waters, M.L. J. Am. Chem. Soc. 126, 2028–2034 (2004).
- 11.
Zhong, W. et al. Proc. Natl. Acad. Sci. USA 95, 12088–12093 (1998).
- 12.
Jacobs, S.A. & Khorasanizadeh, S. Science 295, 2080–2083 (2002).
- 13.
Hughes, R.M. & Waters, M.L. J. Am. Chem. Soc. 127, 6518–6519 (2005).
- 14.
Schweitzer, B.A. & Kool, E.T. J. Org. Chem. 59, 7238–7242 (1994).
- 15.
Kool, E.T. Annu. Rev. Biophys. Biomol. Struct. 30, 1–22 (2001).
- 16.
Moran, S., Ren, R.X.F. & Kool, E.T. Proc. Natl. Acad. Sci. USA 94, 10506–10511 (1997).
- 17.
Delaney, J.C. et al. Proc. Natl. Acad. Sci. USA 100, 4469–4473 (2003).
- 18.
Kim, T.W., Delaney, J.C., Essigmann, J.M. & Kool, E.T. Proc. Natl. Acad. Sci. USA 102, 15803–15808 (2005).
- 19.
Henry, A.A. & Romesberg, F.E. Curr. Opin. Chem. Biol. 7, 727–733 (2003).
- 20.
Hirao, I. Curr. Opin. Chem. Biol. 10, 622–627 (2006).
- 21.
Breslow, R., Zhang, X. & Huang, Y. J. Am. Chem. Soc. 119, 4535–4536 (1997).
Acknowledgements
E.T.K. acknowledges US National Institutes of Health grants GM072705 and GM63587, and M.L.W. acknowledges a US National Science Foundation Career Award (CHE-0094068) and NIH grant GM071589 for support of work with model systems.
Author information
Affiliations
Eric T. Kool is in the Department of Chemistry, Stanford University, Stanford, California 94305, USA. kool@stanford.edu
- Eric T Kool
Marcey L. Waters is in the Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. mlwaters@email.unc.edu
- Marcey L Waters
Authors
Search for Eric T Kool in:
Search for Marcey L Waters in:
Competing interests
The authors declare no competing financial interests.
Rights and permissions
To obtain permission to re-use content from this article visit RightsLink.