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A road map of cellular protein homeostasis

A powerful technology called global protein stability profiling allows rates of protein turnover to be determined for a substantial fraction of the human proteome in a single experiment. This approach sets the stage for systems-level analyses of the dynamics of the mammalian proteome.

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Figure 1: Global protein stability profiling.

Kim Caesar

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Ang, X., Harper, J. A road map of cellular protein homeostasis. Nat Chem Biol 5, 9–11 (2009). https://doi.org/10.1038/nchembio0109-9

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