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A TR(i)P in the air

Nature Chemical Biology volume 7, pages 661–663 (2011)Cite this article

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A Corrigendum to this article was published on 18 October 2011

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Monitoring oxygen (O2) levels is essential to optimizing aerobic metabolism and ensuring proper biological processes in most eukaryotes. The spice chemosensor TRPA1 is a previously unidentified O2 sensor in the mammalian sensory nervous system that warns against hyperoxia and hypoxia.

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Figure 1: Hyperoxia and hypoxia activate the chemosensor TRPA1.

Katie Vicari

Change history

  • 23 September 2011

    In the version of this article initially published, on p.661, column 3, mustard oil was mistakenly grouped with cinnamaldehyde as an α,β-unsaturated carbonyl. The sentence should have read "...whereas α,β-unsaturated carbonyls such as cinnamaldehyde and the structurally unrelated mustard oil activate TRPA1 through the formation of Michael adducts..." The error has been corrected in the HTML and PDF versions of the article.

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  1. Peter M. Zygmunt is in the Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden.,

    Peter M Zygmunt

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  1. Peter M Zygmunt
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Correspondence to Peter M Zygmunt.

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Zygmunt, P. A TR(i)P in the air. Nat Chem Biol 7, 661–663 (2011). https://doi.org/10.1038/nchembio.669

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