To find out which metabolites bind to which proteins, one does not need to start with a hypothesis: it is now easiest just to do the experiments. As it turns out, some metabolites are quite promiscuous, at least in yeast.
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Kell, D. Metabolites do social networking. Nat Chem Biol 7, 7–8 (2011). https://doi.org/10.1038/nchembio.505
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DOI: https://doi.org/10.1038/nchembio.505
