Therapeutic drug monitoring is vital for maintaining drug concentrations within the body in real time, maximizing therapeutic effects while minimizing the risk of harmful overdosing or wasteful underdosing. Semisynthetic fusion proteins now provide a straightforward strategy for drug monitoring by simply taking a picture of glowing paper.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Cronstein, B.N. Pharmacol. Rev. 57, 163–172 (2005).
Asselin, B.L. et al. Blood 118, 874–883 (2011).
Saint-Marcoux, F., Sauvage, F.-L. & Marquet, P. Anal. Bioanal. Chem. 388, 1327–1349 (2007).
Griss, R. et al. Nat. Chem. Biol. 10, 598–603 (2014).
Martinez, A.W., Phillips, S.T. & Whitesides, G.M. Anal. Chem. 82, 3–10 (2010).
Santhiago, M. et al. Bioanalysis 6, 89–106 (2014).
Nery, E.W. & Kubota, L.T. Anal. Bioanal. Chem. 405, 7573–7595 (2013).
Zhou, F., Noor, M.O. & Krull, U.J. Anal. Chem. 86, 2719–2726 (2014).
Yang, X. et al. Lab Chip 12, 274–280 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Ge, L., Yu, J. Bright lights yield drug readout. Nat Chem Biol 10, 490–491 (2014). https://doi.org/10.1038/nchembio.1562
Published:
Issue Date:
DOI: https://doi.org/10.1038/nchembio.1562
This article is cited by
-
Photonic monitoring of treatment during infection and sepsis: development of new detection strategies and potential clinical applications
Analytical and Bioanalytical Chemistry (2018)
-
Erratum: Drug Monitoring: Bright lights yield drug readout
Nature Chemical Biology (2014)