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Stereoselective synthesis

Molecular editing of carbohydrates

Deoxygenation reactions have been used to convert biomass-derived carbohydrates into useful platform chemicals. Now, a method has been described that can selectively excise C–O bonds to produce valuable chiral synthons.

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Figure 1: Reduction of biomass-derived carbohydrates.

References

  1. Corma, A., Iborra, S. & Velty, A. Chem. Rev. 107, 2411–2502 (2007).

    Article  CAS  Google Scholar 

  2. Luterbacher, J. S., Alonso, D. M. & Dumesic, J. A. Green. Chem. 16, 4816–4838 (2014).

    Article  CAS  Google Scholar 

  3. Adduci, L. L., Bender, T. A., Dabrowski, J. A. & Gagné M. R. Nature Chem. 7, 576–581 (2015).

    Article  CAS  Google Scholar 

  4. Chheda, J. N., Huber, G. W. & Dumesic, J. A. Angew. Chem. Int. Ed. 46, 7164–7183 (2007).

    Article  CAS  Google Scholar 

  5. van Putten, R. J. et al. Chem. Rev. 113, 1499–1597 (2013).

    Article  CAS  Google Scholar 

  6. Ruppert, A. M., Weinberg, K. & Palkovits, R. Angew. Chem. Int. Ed. 51, 2564–2601 (2012).

    Article  CAS  Google Scholar 

  7. Hollingsworth, R. I. & Wang, G. Chem. Rev. 100, 4267–4282 (2000).

    Article  CAS  Google Scholar 

  8. Adduci, L. L., McLaughlin, M. P., Bender, T. A., Becker, J. J. & Gagné, M. R. Angew. Chem. Int. Ed. 53, 1646–1649 (2014).

    Article  CAS  Google Scholar 

  9. Houghton, A. Y., Hurmalainen, J., Mansikkamäki, A., Piers, W. E. & Tuononen, H. M. Nature. Chem. 6, 983–988 (2014).

    Article  CAS  Google Scholar 

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Correspondence to Andrew McNally.

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McNally, A. Molecular editing of carbohydrates. Nature Chem 7, 539–541 (2015). https://doi.org/10.1038/nchem.2289

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