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DNA nanotechnology

The world's smallest assembly line

Nature Chemistry volume 4, pages 79–80 (2012)Cite this article

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Two separate studies show how DNA tiles can be used in automated assembly processes: one system self-replicates, the second assembles the output of a molecular computation.

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Figure 1: DNA tiles (A and B) are programmed to assemble into a prototype pattern through hybridization.
Figure 2: An assembly of DNA tiles is able to divide by three binary numbers represented by DNA tiles, with sticky-ended DNA strands representing '0' and '1' domains.

References

  1. Rae, J. B. American Automobile Manufacturers: The First Forty Years (Chilton, 1959)

    Google Scholar 

  2. Seeman, N. Nature 421, 427–431 (2003).

    Article  PubMed Central  Google Scholar 

  3. Wang, T. et al. Nature 478, 225–229 (2011).

    Article  CAS  PubMed Central  Google Scholar 

  4. Kuzuya, A. et al. Nano Lett. 7, 1757–1763 (2007).

    Article  CAS  PubMed Central  Google Scholar 

  5. Chakraborty, B. et al. Chem. Sci. 3, 168–176 (2012).

    Article  CAS  PubMed Central  Google Scholar 

  6. Jonoska, N., Liao, S. & Seeman, N. C. in Aspects of Molecular Computing (eds Jonoska, N., Păun, G. & Rozenberg, G.) 219–240 (Lecture Notes in Computer Science series 2950, Springer, 2004).

    Book  Google Scholar 

  7. Glotzer, S. C. Science 85, 419–420 (2004).

    Article  Google Scholar 

  8. Glotzer, S. C. & Solomon, M. J. Nature Mater. 6, 557–562 (2007).

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Chemical Engineering, University of Michigan, Ann Arbor, 48109, Michigan, USA

    Greg van Anders & Sharon C. Glotzer

  2. Department of Materials Science & Engineering, University of Michigan, Ann Arbor, 48109, Michigan, USA

    Sharon C. Glotzer

Authors
  1. Greg van Anders
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  2. Sharon C. Glotzer
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Correspondence to Sharon C. Glotzer.

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van Anders, G., Glotzer, S. The world's smallest assembly line. Nature Chem 4, 79–80 (2012). https://doi.org/10.1038/nchem.1251

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