The eukaryotic cell uses two complex machineries to degrade unwanted proteins. The first is the ubiquitin–proteasome system and the second is autophagy. A new study contributes to our understanding of how the two systems interconnect to coordinate protein degradation.
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Martens, S., Bachmair, A. How cells coordinate waste removal through their major proteolytic pathways. Nat Cell Biol 17, 841–842 (2015). https://doi.org/10.1038/ncb3198
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DOI: https://doi.org/10.1038/ncb3198
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