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Seeing the Warburg effect in the developing retina

Nature Cell Biology volume 14, pages 790–791 (2012)Cite this article

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Proliferating cells of the Xenopus laevis retina facultatively use aerobic glycolysis instead of oxidative phosphorylation. This demonstrates that the metabolic rewiring usually associated with the Warburg effect in tumorigenesis may be a more widespread feature of proliferative metabolism than generally appreciated.

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Figure 1: Pathways for glycogen catabolism in proliferating cells.

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Authors and Affiliations

  1. Brian P. Fiske and Matthew G. Vander Heiden are at the Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA,

    Brian P. Fiske & Matthew G. Vander Heiden

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  1. Brian P. Fiske
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  2. Matthew G. Vander Heiden
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Correspondence to Matthew G. Vander Heiden.

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Fiske, B., Vander Heiden, M. Seeing the Warburg effect in the developing retina. Nat Cell Biol 14, 790–791 (2012). https://doi.org/10.1038/ncb2554

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