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Phosphatidylserine promotes polar Cdc42 localization

Nature Cell Biology volume 13, pages 1387–1388 (2011)Cite this article

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The establishment and maintenance of cell polarity requires targeted recruitment of polarity regulators to the plasma membrane. Phosphatidylserine is now shown to have a key role in polarization of yeast cells and the localization of the central polarity regulator Cdc42.

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Figure 1: Schematic representation of the processes contributing to Cdc42 and phosphatidylserine localization during polarization of yeast cells.

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Authors and Affiliations

  1. Tina Freisinger and Roland Wedlich-Söldner are at the Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany,

    Tina Freisinger & Roland Wedlich-Söldner

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  1. Tina Freisinger
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  2. Roland Wedlich-Söldner
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Correspondence to Roland Wedlich-Söldner.

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The authors declare no competing financial interests.

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Freisinger, T., Wedlich-Söldner, R. Phosphatidylserine promotes polar Cdc42 localization. Nat Cell Biol 13, 1387–1388 (2011). https://doi.org/10.1038/ncb2382

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