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Signalling by adhesion receptors

Nature Cell Biology volume 2, pages E225–E229 (2000)Cite this article

Abstract

Over the past twenty years, intensive research has enabled us to identify components of specific signalling pathways downstream of an array of adhesion and growth-factor receptors. The first Gordon Research Conference on `Signalling by Adhesion Receptors', which took place in Newport, Rhode Island, USA (23–28 July 2000), focused on these findings.

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Figure 1: Cooperativity between growth-factor receptors and integrins.
Figure 2: Rho couples sustained MAPK activation with expression of cyclin D.
Figure 3: Wnt and cadherin pathways. Two receptor families that use β-catenin are shown — the Frizzled-family proteins and the cadherins.

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Authors and Affiliations

  1. the Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, 19111, Pennsylvania, USA

    Sarah J. Fashena

  2. the Beth Israel Deaconess Medical Center/Harvard Medical School, 330 Brookline Avenue, Boston, 02215, Massachusetts, USA

    Sheila M. Thomas

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  1. Sarah J. Fashena
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  2. Sheila M. Thomas
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Fashena, S., Thomas, S. Signalling by adhesion receptors. Nat Cell Biol 2, E225–E229 (2000). https://doi.org/10.1038/35046654

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