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Hopeful monsters and morphogens at the beach

Abstract

The Santa Cruz Developmental Biology Conference (August 15–19, 2002) provided the latest insights into how a single cell is transformed into a complex organism. Organisms that flower, slither, walk and fly continue to provide new insights into the cell biological and molecular mechanisms that control cell movement, signalling pathways and post-transcriptional regulation; hopeful monsters sit at our doorstep to provide new insight into evolutionary change and human disease.

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Figure 1: Three steps in planar cell polarity signalling leading to morphological orientation.
Figure 2: Changes in protein sequence mediate macroevolution.

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Niswander, L., Anderson, K. Hopeful monsters and morphogens at the beach. Nat Cell Biol 4, E259–E262 (2002). https://doi.org/10.1038/ncb1102-e259

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