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Hauling t-SNAREs on the microtubule highway

Microtubule-mediated transport is essential for neuronal viability, neurite extension, synapse formation and synaptic function. Now a new kinesin receptor, syntabulin, has been identified that controls transport of the t-SNARE syntaxin along microtubules.

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Figure 1: Microtubule-mediated transport of synaptic components.
Figure 2: Domain structures of syntabulin and ocsyn.

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Zhai, R., Bellen, H. Hauling t-SNAREs on the microtubule highway. Nat Cell Biol 6, 918–919 (2004). https://doi.org/10.1038/ncb1004-918

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