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Asymmetry across species

Nature Cell Biology volume 1, pages E42–E44 (1999)Cite this article

Abstract

In both worms and flies, asymmetric cell divisions involve the protein Bazooka/PAR-3, which is required for the asymmetric segregation of cell-fate determinants. However, differential distribution of a determinant between daughter cells may be achieved by different means in alternative developmental settings.

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Figure 1: Model for bazooka function in neuroblasts.
Figure 2: In a mitotic Drosophila neuroblast, during prophase, the Miranda, Prospero and Staufen proteins and prospero mRNA probably form a complex at the apical cortex, and they co-localize with the Bazooka and Inscuteable proteins.

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Authors and Affiliations

  1. Departments of Physiology and Biochemistry, Howard Hughes Medical Institute, UCSF, Box 0725, San Francisco, 94143-0725, California, USA

    Yuh-Nung Jan & Lily Yeh Jan

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  1. Yuh-Nung Jan
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  2. Lily Yeh Jan
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Correspondence to Yuh-Nung Jan.

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Jan, YN., Jan, L. Asymmetry across species. Nat Cell Biol 1, E42–E44 (1999). https://doi.org/10.1038/10036

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