Signalling by growth factors, such as fibroblast growth factor (FGF), is critical for many of the morphogenetic events that shape the early embryo — including limb development. Recent findings regarding the regulation of FGF during limb development bridge the divide between results gained from in vitro biochemistry and the realities of in vivo development.
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Dudley, A., Tabin, C. Deconstructing phosphatases in limb development. Nat Cell Biol 5, 499–501 (2003). https://doi.org/10.1038/ncb0603-499
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DOI: https://doi.org/10.1038/ncb0603-499
