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Pore-ing the right dose

Dosage compensation in Drosophila melanogaster is distinguished by the hypertranscription of the male X chromosome. New findings show that this process requires the nuclear pore complex.

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Figure 1: NPC-association with the Drosophila DCC may function to create and maintain chromatin domains that stimulate transcription.

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Brown, C., Silver, P. Pore-ing the right dose. Nat Cell Biol 8, 430–431 (2006). https://doi.org/10.1038/ncb0506-430

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