The specificity of cytoskeleton-mediated cargo transport is critical for cell polarization. The Egalitarian protein — required for the localization of mRNAs and proteins to the oocyte of the Drosophila melanogaster ovary — is now reported to interact with an integral component of the dynein motor complex, the dynein light chain Dlc1.
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Pearson, J., González-Reyes, A. Egalitarian and the case of the missing link. Nat Cell Biol 6, 381–383 (2004). https://doi.org/10.1038/ncb0504-381
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DOI: https://doi.org/10.1038/ncb0504-381
