Sprouty proteins are antagonists of receptor tyrosine kinase (RTK) signalling in a number of developmental and physiological processes. A collection of work indicates that Sprouty proteins negatively and positively modulate RTK-induced signalling pathways through various mechanisms, thereby combining a variety of cellular functions in one molecule.
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Christofori, G. Split personalities: the agonistic antagonist Sprouty. Nat Cell Biol 5, 377–379 (2003). https://doi.org/10.1038/ncb0503-377
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DOI: https://doi.org/10.1038/ncb0503-377
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