One of the earliest structural changes in cloning by nuclear transfer is the disassembly of the nucleolus. The first insights into the molecular mechanisms of this event have now emerged and the results have tantalising implications for nucleolar architecture.
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Misteli, T. A nucleolar disappearing act in somatic cloning. Nat Cell Biol 5, 183–184 (2003). https://doi.org/10.1038/ncb0303-183
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DOI: https://doi.org/10.1038/ncb0303-183
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