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Thrilling transcription through threonine phosphorylation

Covalent modifications of histone tails are highly correlated with different states of gene expression. Although the biological significance of many such modifications has been elucidated, the physiological role of Thr 11 phosphorylation on histone H3 (H3T11) has remained elusive.

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Figure 1: Schematic representation depicting the sequence of events following association of androgen receptors (AR) with PRK1.

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Croce, L., Shiekhattar, R. Thrilling transcription through threonine phosphorylation. Nat Cell Biol 10, 5–6 (2008). https://doi.org/10.1038/ncb0108-5

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