Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Reconstructing genetic networks in yeast

By combining data from gene expression and DNA-binding experiments, a computational algorithm identifies the genetic regulatory network in yeast.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Schematic describing the GRAM algorithm.

References

  1. Bar-Joseph, Z. et al. Nat. Biotechnol. 21, 1337–1342 (2003).

    Article  CAS  Google Scholar 

  2. Chu, S. et al. Science 282, 699–705 (1998).

    Article  CAS  Google Scholar 

  3. Ren, B. et al. Science 290, 2306–2309 (2000).

    Article  CAS  Google Scholar 

  4. Iyer, V.R. et al. Nature 409, 533–538 (2001).

    Article  CAS  Google Scholar 

  5. Horak, C.E. et al. Genes Dev. 16, 3017–3033 (2002).

    Article  CAS  Google Scholar 

  6. Lee, T.I. et al. Science 298, 799–804 (2002).

    Article  CAS  Google Scholar 

  7. Qian, J., Dolled-Filhart, M., Lin, J., Yu, H. & Gerstein, M. J. Mol. Biol. 314, 1053–1066 (2001).

    Article  CAS  Google Scholar 

  8. Ihmels, J. et al. Nat. Genet. 31, 370–377 (2002).

    Article  CAS  Google Scholar 

  9. Pilpel, Y., Sudarsanam, P. & Church, G.M. Nat. Genet. 29, 153–159 (2001).

    Article  CAS  Google Scholar 

  10. Yu, H., Luscombe, N.M., Qian, J. & Gerstein, M. Trends Genet. 19, 422–427 (2003).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhang, Z., Gerstein, M. Reconstructing genetic networks in yeast. Nat Biotechnol 21, 1295–1297 (2003). https://doi.org/10.1038/nbt1103-1295

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt1103-1295

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing