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Tracing cancer networks with phosphoproteomics

A mass-spectrometry approach for identifying downstream events in cancer signaling pathways may help to tailor therapies to individual patients.

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Figure 1: Identification of (Ser)/(Thr) phosphorylation substrates in core cancer signaling pathways.

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Correspondence to David B Solit or Ingo K Mellinghoff.

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Solit, D., Mellinghoff, I. Tracing cancer networks with phosphoproteomics. Nat Biotechnol 28, 1028–1029 (2010). https://doi.org/10.1038/nbt1010-1028

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