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Phosphoproteomics finds its timing

The temporal dynamics of EGFR signaling has been studied on a broad scale with mass spectrometry.

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Figure 1: Cells are cultured for several divisions in the presence of one of three isotopically labeled forms of arginine so that all arginine-containing proteins become labeled.

Bob Crimi

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Johnson, S., Hunter, T. Phosphoproteomics finds its timing. Nat Biotechnol 22, 1093–1094 (2004). https://doi.org/10.1038/nbt0904-1093

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