Reducing a cytokine's affinity for its receptor increases its ability to be reused and recycled, and could enhance its therapeutic potency.
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Robinson, C. Reduce, reuse, and recycle. Nat Biotechnol 20, 879–880 (2002). https://doi.org/10.1038/nbt0902-879
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DOI: https://doi.org/10.1038/nbt0902-879
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