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The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions

Nature Biotechnology volume 16, pages 633–638 (1998)Cite this article

Abstract

The analysis of macromolecular interactions is an essential element of biomedical research. Flow cytometry is uniquely capable of making sensitive and quantitative measurements of molecular interactions. These measurements can be made in real time with subsecond kinetic resolution using purified biomolecules or living cells. Combined with automated sample handling, these features make flow cytometry a versatile and robust technology for the analysis of molecular interactions.

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Authors and Affiliations

  1. National Flow Cytometry Resource and Life Sciences Division, Los Alamos National Laboratory, Los Alamos, NM, 87545

    John P. Nolan & Larry A. Sklar

  2. Cancer Center and Department of Pathology, University of New Mexico, Albuquerque, NM, 87131

    Larry A. Sklar

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  1. John P. Nolan
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  2. Larry A. Sklar
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Nolan, J., Sklar, L. The emergence of flow cytometry for sensitive, real-time measurements of molecular interactions. Nat Biotechnol 16, 633–638 (1998). https://doi.org/10.1038/nbt0798-633

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