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Developing safe therapies from human pluripotent stem cells

Nature Biotechnology volume 27, pages 606–613 (2009)Cite this article

Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.

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Figure 1: Schematic showing processing and manufacturing steps involved in developing a stem cell product.

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Author information

Authors and Affiliations

  1. Melissa K. Carpenter is at the Carpenter Group, San Diego, California, USA m_carpenter@mac.com,

    Melissa K Carpenter

  2. Joyce Frey-Vasconcells is at Pharmanet Consulting, Princeton, New Jersey, USA,

    Joyce Frey-Vasconcells

  3. Mahendra S. Rao is at Invitrogen Corp., Frederick, Maryland, USA.,

    Mahendra S Rao

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  1. Melissa K Carpenter
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  2. Joyce Frey-Vasconcells
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  3. Mahendra S Rao
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Carpenter, M., Frey-Vasconcells, J. & Rao, M. Developing safe therapies from human pluripotent stem cells. Nat Biotechnol 27, 606–613 (2009). https://doi.org/10.1038/nbt0709-606

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