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Jump-starting cancer gene discovery

Nature Biotechnology volume 27, pages 251–252 (2009)Cite this article

Targeting transposon mutagenesis to a specific tissue facilitates screening for tumor-associated genes and tracking of tumor lineages.

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Figure 1: A conditional Sleeping Beauty transposase (SB11) allele is crossed to a Cre transgene under control of the albumin-gene (Alb) promoter to specifically induce expression in the liver.

Kim Caesar

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Authors and Affiliations

  1. Anthony Uren and Anton Berns are in the Division of Molecular Genetics, The Cancer Genomics Centre (CGC), The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands. a.berns@nki.nl,

    Anthony Uren & Anton Berns

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  1. Anthony Uren
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  2. Anton Berns
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Uren, A., Berns, A. Jump-starting cancer gene discovery. Nat Biotechnol 27, 251–252 (2009). https://doi.org/10.1038/nbt0309-251

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