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Coiled coils unspring protein origami

Self-assembling sequences of protein coiled coils create polyhedral nanostructures for advanced applications in biomedicine, chemistry and materials science.

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Figure 1: Computational and experimental framework for coiled-coil protein origami.

References

  1. Ljubetič, A. et al. Nat. Biotechnol. 35, 1094–1101 (2017)

    Article  Google Scholar 

  2. Gradišar, H. et al. Nat. Chem. Biol. 9, 362–366 (2013).

    Article  Google Scholar 

  3. Crick, F.H.C. Nature 170, 882–883 (1952).

    Article  CAS  Google Scholar 

  4. Landschulz, W.H., Johnson, P.F. & McKnight, S.L. Science 240, 1759–1764 (1988).

    Article  CAS  Google Scholar 

  5. Hopfner, K.P. et al. Nature 418, 562–566 (2002).

    Article  CAS  Google Scholar 

  6. Harbury, P.B., Plecs, J.J., Tidor, B., Alber, T. & Kim, P.S. Science 282, 1462–1467 (1998).

    Article  CAS  Google Scholar 

  7. Sacca, B. & Niemeyer, C.M. Angew. Chem. Intl. Edn. Engl. 51, 58–66 (2012).

    Article  CAS  Google Scholar 

  8. Lai, Y.T. et al. Sci. Adv. 2, e1501855 (2016).

    Article  Google Scholar 

  9. Brunette, T.J. et al. Nature 528, 580–584 (2015).

    Article  CAS  Google Scholar 

  10. Hura, G.L. et al. Nat. Methods 10, 453–454 (2013).

    Article  CAS  Google Scholar 

Download references

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Correspondence to John A Tainer.

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Hura, G., Tainer, J. Coiled coils unspring protein origami. Nat Biotechnol 35, 1044–1045 (2017). https://doi.org/10.1038/nbt.4003

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