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An optical probe of synaptic plasticity

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An endogenous protein in the mouse brain is inactivated using a light-sensitive antibody construct.

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Figure 1: CALI-mediated GluA1 inactivation enables dissection of the molecular underpinnings of memory.

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  • 30 March 2017

    In the version of this article initially published, reference 1 was missing the author's first initial. The error has been corrected in the HTML and PDF versions of the article.

References

  1. Takemoto, K. et al. Nat. Biotechnol. 35, 38–47 (2017).

    Article  CAS  Google Scholar 

  2. Jay, D.G. Proc. Natl. Acad. Sci. USA 85, 5454–5458 (1988).

    Article  CAS  Google Scholar 

  3. Mayford, M., Siegelbaum, S.A. & Kandel, E.R. Cold Spring Harb. Perspect. Biol. http://dx.doi.org/10.1101/cshperspect.a005751 (2012).

  4. Lin, J.Y. et al. Neuron 79, 241–253 (2013).

    Article  CAS  Google Scholar 

  5. Kessels, H.W. & Malinow, R. Neuron 61, 340–350 (2009).

    Article  CAS  Google Scholar 

  6. Malenka, R.C. Ann. NY Acad. Sci. 1003, 1–11 (2003).

    Article  CAS  Google Scholar 

  7. Linden, K.G., Liao, J.C. & Jay, D.G. Biophys. J. 61, 956–962 (1992).

    Article  CAS  Google Scholar 

  8. Hayashi-Takagi, A. et al. Nature 525, 333–338 (2015).

    Article  CAS  Google Scholar 

  9. Matsuzaki, M. et al. Nat. Neurosci. 4, 1086–1092 (2001).

    Article  CAS  Google Scholar 

  10. Yang, G., Pan, F. & Gan, W.B. Nature 462, 920–924 (2009).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Ryohei Yasuda.

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Laviv, T., Yasuda, R. An optical probe of synaptic plasticity. Nat Biotechnol 35, 26–27 (2017). https://doi.org/10.1038/nbt.3767

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