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Insulating gene circuits from context by RNA processing

Nature Biotechnology volume 30, pages 1061–1062 (2012)Cite this article

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Two studies find that programmable RNA-processing tools counter the problem of context-dependence in the construction of synthetic biology circuits.

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Figure 1: Synthetic RNA processing buffers against context-dependent variability of circuit output.

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Authors and Affiliations

  1. Department of Biomedical Engineering and Center for BioDynamics, Caleb J. Bashor and James J. Collins are at the Howard Hughes Medical Institute, Boston University, Boston, Massachusetts, USA.,

    Caleb J Bashor & James J Collins

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  1. Caleb J Bashor
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  2. James J Collins
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Correspondence to James J Collins.

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Bashor, C., Collins, J. Insulating gene circuits from context by RNA processing. Nat Biotechnol 30, 1061–1062 (2012). https://doi.org/10.1038/nbt.2411

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